This photo shows the city cardo of Laodicea. Those who evangelized the city and members of the church in that city must have frequented this road.
The city of Laodicea was known for several things. (1) The Lycus valley was the source of a glossy black (raven-colored) wool used in making black cloaks and carpets, for which the city was famous. (2) Laodicea was also the home of a medical school, and the manufacture of collyrium, a famous eyesalve. There is no evidence for William Ramsay’s statement that the eyesalve was made from powdered Phrygian stone, recommended by Galen, though it is possible that this might be true (Anchor Bible Dictionary IV: 230). (3) The city was also near “to the emetic (‘a medicine or other substance that causes vomiting,’ mw) qualities of the soda-ladan warm water from nearby Hierapolis, whose thermal springs ran into the Maeander” (Zondervan Pictorial Bible Dictionary 476). The waters at Hierapolis were thought to be therapeutic because they were hot and the waters from Colossae were refreshing because they were cold. But the waters at Laodicea were “lukewarm.” Notice how each of these things is alluded to in the letter to Laodicea:
I know thy works, that thou art neither cold nor hot: I would thou wert cold or hot. So then because thou art lukewarm, and neither cold nor hot, I will spue thee out of my mouth. Because thou sayest, I am rich, and increased with goods, and have need of nothing; and knowest not that thou art wretched, and miserable, and poor, and blind, and naked: I counsel thee to buy of me gold tried in the fire, that thou mayest be rich; and white raiment, that thou mayest be clothed, and that the shame of thy nakedness do not appear; and anoint thine eyes with eyesalve, that thou mayest see (Rev. 3:15-18).
The church at Laodicea was probably started by one of Paul’s colleagues (most likely Epaphras) during his three-year stay at Ephesus. In addition to being mentioned in Revelation, Laodicea is mentioned in Colossians 2:1. Paul wrote a letter to the church which letter does not exist (Col. 4:16). Epaphras had some connection with the church at Laodicea for Paul writes, “Epaphras, who is one of you, a servant of Christ, saluteth you, always labouring fervently for you in prayers, that ye may stand perfect and complete in all the will of God. For I bear him record, that he hath a great zeal for you, and them that are in Laodicea, and them in Hierapolis” (Col. 4:12-13).